Overview
Dr. Gül focuses on understanding the molecular circadian clock mechanism in mammals. In addition, his group aims to explore how circadian clock gene mutations are linked to various diseases and discover small molecules having potential to use against such diseases. For this purpose, Gül group is conducting interdisciplinary methods by using computer-based drug discovery tools, in vitro and in vivo molecular biology methods.
He has, so far, co-authored 28 peer-reviewed publications, 2 book chapters, and holds 1 patent.
Education:
- 2013 - 2019 PhD Chemical and Biological Engineering Koç University
- 2010 – 2013 MSc Chemistry, Michigan State University
- 2008 – 2010 MSc Chemistry Boğaziçi University
- 2003 – 2008 B.Sc Chemistry Boğaziçi University
Affiliations:
- Beykoz Institute of Life Sciences and Biotechnology, Bezmialem Vakıf University, Turkey
Research Interest
Circadian clock, protein engineering, drug design, biotechnology, molecular biochemistry
Awards / Honors:
TÜBİTAK 3501 Career Development Program (CAREER), 2022
Publications (selected):
- Gul Ş., Akyel Y. K., Gul Z. M., Isin S., Ozcan O., Korkmaz T., Selvi S., Danis I., Ipek O. S., Aygenli F., Taskin A. C., Akarlar B. A., Ozlu N., Ozturk N., Ozturk N., Ünal D. Ö., Guzel M., Turkay M., Okyar A., Kavakli I. H Nature Communications, 13, 6742 (2022).
- Gul Ş., Rahim F., Isin S., Yilmaz F., Ozturk N., Turkay M., Kavakli I. H. Scientific Reports, 11, 18510 (2021).
- Parlak G. C., Camur B. B., Gul Ş., Ozcan O., Baris I., Kavakli I. H Journal of Biological Chemistry, 298(9) (2022).
- Gul Ş., Aydin C., Ozcan O., Gurkan B., Surme S., Baris I., Kavakli I. H Journal of Biological Chemistry, 295(50), 17187-17199 (2020).
- Emre Onat O., Ece Kars M., Gül Ş., Bilguvar K., Wu Y., Özhan A., Aydın C., Nazlı Başak A., Allegra Trusso M., Goracci A., Fallerini C., Renieri A., Casanova J., Itan Y., Atbaşoğlu C. E., Saka M. C., Halil Kavaklı İ., Özçelik T. Journal of Clinical Investigation, 130(7), 3 885-3900 (2020).
- Doruk Y. U., Yarparvar D., Akyel Y. K., Gul Ş., Taskin A. C., Yilmaz F., Baris I., Ozturk N., Türkay M., Ozturk N., Okyar A., Kavakli I. H. Journal of Biological Chemistry 295(11), 3518-3531 (2019)
Grants (Ongoing):
Scientific and Technological Research Council of Turkey (TUBITAK)
